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Castle Biosciences Inc (CSTL)

$34.94
LAST CLOSE · NOV 2

Castle Biosciences sells molecular diagnostic tests that help clinicians diagnose and treat skin cancers and certain other conditions. It last closed at $34.94 on Nov 2. CSTL reports earnings on Thu, Nov 5, 2026.

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Key Stats

Last 12 months
Results
Revenue
$357.3M
+3.2% vs a year ago
Net income
−$19.4M
−5.4% margin
EPS (diluted)
−$0.64
Free cash flow
−$489K
−0.1% margin
Valuation
Market cap
$1.1B
30.5M shares
P/E
–
No P/E while losing money
Price to sales
3.0
Market cap over revenue
Dividend yield
None
No dividend in 12 months
Balance sheet
Cash & equivalents
$62.1M
At Jun 30
Debt
$10.1M
At Jun 30
Shareholder equity
$470.0M
Shares outstanding
30.5M
At Jul 23
Fiscal year endsDecember
ExchangeNasdaq
Financials history
FY2021: $94.1M$94.1MFY2021FY2022: $137.0M$137.0MFY2022FY2023: $219.8M$219.8MFY2023FY2024: $332.1M$332.1MFY2024FY2025: $344.2M$344.2MFY2025

From CSTL's SEC filings, latest 10-Q for the period ending Jun 30, 2026 (filed Jul 30). Last 12 months adds up the four latest quarters.

Next report
Nov 5
2026 · Time not announced
Consensus EPS forecast
-$0.35
$92.8M revenue est.
Year-ago EPS
—
Not on file
Options-implied move
—
Posted about a week before
Analyst consensus
—
No ratings in 90 days
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Analyst Ratings & Price Targets

Analyst Ratings →
Consensus · 90 days
No firm has rated CSTL in the past 90 days.
Average 12-month target
No price targets on CSTL in the past 90 days.
Latest rating changes
BTIGMaintained
Aug 3Buy$44
Roth CapitalInitiated
Jun 25Buy$40
DateFirmActionRatingPrice target
Aug 3BTIGMaintainedBuy$44
Jun 25Roth CapitalInitiatedBuy$40
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Technical Analysis

CSTL · as of the Nov 2 close · updated after every close
Uptrend

The stock is 3% above its 20 day and 2% above its 50 day average. It is 18% above its 200 day average, so the longer trend is still up. Momentum is improving (RSI 52). The nearest support is the 50 day average at $34.23, and the nearest resistance the swing high (Aug 25) at $35.20.

Short trendBullish
Long trendBullish
MomentumImproving
StretchNormal
VolatilityNormal, 5.2%/day
Key levels
$44.2852 week high+26.7%
$36.82Pivot R1+5.4%
$35.64Pivot+2.0%
$35.20Swing high (Aug 25)+0.7%
$34.94Last close
$34.2350 day average−2.0%
$34.14Swing low (Sep 30)−2.3%
$34.0020 day average−2.7%
$33.76Pivot S1−3.4%
$30.03100 day average−14.1%
$28.50200 day average−18.4%
$17.7252 week low−49.3%
Indicators
RSI (14)51.82Middle of its rangeNeutral
MACD0.61Above its signal lineBullish
Stochastic73.7Middle of its rangeNeutral
ADX (14)21.5Weak trend
Williams %R-53.7Oversold below −80, overbought above −20Neutral
CCI (20)90.3Oversold below −100, overbought above 100Neutral
Rate of change+8.6%Change over 10 sessionsBullish
ATR (14)$1.80Typical daily range, 5.2% of price
MA 10Above
MA 20Above
MA 50Above
MA 100Above
MA 200Above
What happened before, for CSTL

What happened before

See how CSTL did after each of today's signals in the past: how often it was higher 10 sessions later, and the typical move, next to its usual record.

Earnings in 2 daysSignals right before a report are less reliable. The report can override them.
November seasonalityHow CSTL usually does this month. See Seasonality

Calculated from daily prices after each close. Signals describe the chart, not where the stock will go. Past patterns often fail. Not investment advice.

Seasonality

How CSTL has done in each calendar month: the average and median return, how often each month finished higher, and every year since 2019.

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See the stocks that usually rise in November →

Whale Options Flow

90D

No whale options trades in CSTL in the last 90 days.

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CSTL Institutional Ownership

Hedge fund holdings →
Funds holding
176
−10 vs Q1 2026
Held by funds
89.5%
−0.9 pts vs Q1 2026
Buying vs selling
98 / 84
21 new · 30 sold out
Shares held
27.3M
−268K vs Q1 2026
Top holders · Q2 2026
3.3M shares10.78% of company$78.5M+309K
2.8M shares9.09% of company$66.3M+20K
1.7M shares5.65% of company$41.2M−43K
1.2M shares4.01% of company$29.3M+49K
919K shares3.01% of company$22K+434K
841K shares2.75% of company$20.1M−21K
825K shares2.70% of company$19.7M−116K
822K shares2.69% of company$19.6M+53K
811K shares2.66% of company$19.9M0
796K shares2.61% of company$19.0M+68K
#FundSharesOf companyValueChange
1BlackRock, Inc.3.3M10.78%$78.5M+309KAdded
2Rtw Investments, LP2.8M9.09%$66.3M+20KAdded
3Principal Financial Group Inc1.7M5.65%$41.2M−43KTrimmed
4Vanguard Capital Management LLC1.2M4.01%$29.3M+49KAdded
5Acadian Asset Management LLC919K3.01%$22K+434KAdded
6Vanguard Portfolio Management LLC841K2.75%$20.1M−21KTrimmed
7Summit Partners Public Asset Management, LLC825K2.70%$19.7M−116KTrimmed
8State Street Corp822K2.69%$19.6M+53KAdded
9Allianz Asset Management GmbH811K2.66%$19.9M0No change
10Geode Capital Management, LLC796K2.61%$19.0M+68KAdded
Biggest buyers
Biggest sellers
Filed so far for Q3 2026 · 43 funds changed their position

From SEC Form 13F filings by funds managing over $100 million, as of Jun 30, 2026. Changes compare each fund with its own Q1 2026 filing. "Held by funds" adds up the shares every 13F filer reported, over shares outstanding. Filings come up to 45 days after the quarter ends. Not investment advice.

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Paper trading

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CSTL in the AI portfolios
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Macro & Market News

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StreetAlpha hasn't covered CSTL in an article yet. Here's the latest on the wider market.

CSTL Congress Trades

All congress trades →
Trades, 12 months
0
Buys
0
Sells
0
People
0
Last filed Apr 17
Who traded CSTL · since 2020
Latest 3 filings
Josh GottheimerSell (partial)
$1K – $15KTraded Mar 15, 2022Filed Apr 17, 2022
$1K – $15KTraded Dec 23, 2020Filed Jan 11, 2021
$1K – $15KTraded Dec 21, 2020Filed Jan 7, 2021
PersonTypeAmountTradedFiledDelay
Josh GottheimerD · NJSell (partial)$1K – $15KMar 15, 2022Apr 17, 202233 d
Gilbert CisnerosD · CABuy$1K – $15KDec 23, 2020Jan 11, 202119 d
Josh GottheimerD · NJBuy$1K – $15KDec 21, 2020Jan 7, 202117 d

Members of Congress and senior officials report trades up to 45 days later, as dollar ranges. Filings show a trade happened, not why. Not investment advice.

About Castle Biosciences

Castle Biosciences is a molecular diagnostics company based in Friendswood, Texas. It offers laboratory tests that help clinicians diagnose and manage treatment for skin cancers, Barrett's esophagus, uveal melanoma and atopic dermatitis. Its tests analyze patient samples to help estimate risk, guide treatment decisions and support diagnosis, and they are used by clinicians caring for these patients.

Headquarters
Friendswood, TX