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Ionis Pharmaceuticals Inc · 13F filings

IONS Institutional Ownership

Holdings as of Jun 30, 2026From SEC Form 13FUpdated

Who owns Ionis Pharmaceuticals Inc and what the big funds did with it last quarter, from every SEC 13F filing. 525 funds reported holding IONS at Jun 30, 2026, together owning 116.8% of the company.

← IONS stock page

Fund sentiment
Strongly bullish
Strongly bearishNeutralStrongly bullish
  • ▲271 buying vs 213 selling
  • ▲Held by funds +4.5 pts
  • ▲Funds holding +17
  • ●Superinvestors: 2 added, 2 cut
  • ▲Put/call 1.89 to 0.40

What the filings show, not a forecast. Positions can be up to 45 days old and leave out short sales.

Funds holding525+17 vs Q1 2026
Held by funds116.8%+4.5 pts
Value held$14.3B194M shares
Put/call ratio0.40down from 1.89

Funds holding and ownership

8 quarters
Q3 2024: 370 fundsQ3 '24Q4 2024: 369 fundsQ4 '24Q1 2025: 356 fundsQ1 '25Q2 2025: 376 fundsQ2 '25Q3 2025: 451 fundsQ3 '25Q4 2025: 513 fundsQ4 '25Q1 2026: 508 fundsQ1 '26Q2 2026: 525 fundsQ2 '26116.8% owned
Funds holdingHeld by funds %

Quarter over quarter

all 13F filers
Q2 2026This quarterQ1 2026Change
Funds holding525508+3.3%
In funds' top 101015−33.3%
13F shares194M187M+4.0%
Held by funds116.8%112.3%+4.5 pts
New positions6866+3.0%
Increased203177+14.7%
Reduced163156+4.5%
Sold out5077−35.1%
Calls (shares)2.2M292K+665.5%
Puts (shares)892K552K+61.7%
Put/call ratio0.401.89−78.9%

Buyers vs sellers

adding or new vs cutting or sold out
Q4 2024: 163 buyingQ4 2024: 178 sellingQ4 '24Q1 2025: 153 buyingQ1 2025: 185 sellingQ1 '25Q2 2025: 202 buyingQ2 2025: 169 sellingQ2 '25Q3 2025: 252 buyingQ3 2025: 156 sellingQ3 '25Q4 2025: 272 buyingQ4 2025: 186 sellingQ4 '25Q1 2026: 243 buyingQ1 2026: 233 sellingQ1 '26Q2 2026: 271 buyingQ2 2026: 213 sellingQ2 '26
Buying 271Selling 213latest quarter

Superinvestors in IONS

All superinvestors →

Who owns IONS

share of fund held shares
  • Index and passive funds20.4%
  • Active managers and hedge funds64.2%
  • Banks and brokers12.1%
  • Pensions, insurers and other3.3%

The top 10 holders own 52.7% of all IONS shares that funds reported. Groups are our own grouping of filers by name.

Put/call ratio

funds' options, market makers left out
1.00Q3 2024: 0.71Q3 '24Q4 2024: 0.99Q4 '24Q1 2025: 0.23Q1 '25Q2 2025: 0.28Q2 '25Q3 2025: 0.11Q3 '25Q4 2025: 0.65Q4 '25Q1 2026: 1.89Q1 '26Q2 2026: 0.40Q2 '260.40

Above 1 means funds hold more puts than calls, a sign of hedging or bets on a fall. Options are valued at the underlying shares.

Filed so far for Q3 2026

135 funds changed their position

🔒 Free account: see all 20.

Top holders

Q2 2026
#FundOf companySharesValueChange
1Fmr LLC14.82%24.6M$2B+75K
2Capital World Investors13.04%21.7M$1.7B+483K
3BlackRock, Inc.6.44%10.7M$849M+262K
4Vanguard Portfolio Management LLC4.73%7.9M$623M+51K
5Wellington Management Group LLP4.60%7.7M$607M+1.3M
6Vanguard Capital Management LLC4.34%7.2M$572M+93K
7Two Sigma Investments, LP3.76%6.3M$496M+395K
8Royal Bank of Canada3.72%6.2M$490M+2.4M
9Focus Partners Wealth3.11%5.2M$8.1M−103K
10Picton Mahoney Asset Management3.01%5M$7.8M+5M
🔒 15 more top holders. Create a free account or sign in to see them.

IONS institutional ownership FAQ

Who owns the most IONS stock?

In Q2 2026 13F filings the largest holder of IONS was Fmr LLC, followed by Capital World Investors and BlackRock, Inc.. Index fund managers are usually the biggest holders of large companies.

What percentage of IONS is owned by institutions?

Funds that file 13F reports held 116.8% of IONS's shares at Jun 30, 2026, compared with 112.3% a quarter earlier. That counts every manager with more than $100 million in US stocks.

Are hedge funds buying IONS?

In Q2 2026, 271 funds bought IONS (68 of them new positions) and 213 sold (50 sold out completely). Among well known investors, 2 added and 2 cut. Our fund sentiment for IONS is strongly bullish.

What is IONS's institutional put/call ratio?

Funds reported $70.8M of IONS puts against $177M of calls, a put/call ratio of 0.40 (1.89 the quarter before). Market makers and bank trading desks are left out, since their options are mostly hedges.

How current is this IONS ownership data?

13F filings show holdings at the end of each quarter and are due within 45 days, so positions can be up to six weeks old when they appear. We add each new filing within minutes, and the "filed so far" list shows funds that have already reported the next quarter.

For informational and educational purposes only. Not investment advice, and not a recommendation to buy or sell any security. Fund sentiment summarises what 13F filings show and is not a forecast. Holdings come from SEC Form 13F filings as reported and show positions at the end of the quarter, up to 45 days before the filing. A 13F leaves out short positions, cash, bonds and most foreign holdings. See all hedge fund holdings.