Ionis Pharmaceuticals Inc (IONS) is a Healthcare stock tracked by StreetAlpha. It last closed at $43.30 on Oct 8, down 26.31% on the day. IONS reports earnings on Wed, Nov 4, 2026. The average 12-month price target from 11 analysts is $81.82 (+89.0% from the last close), with a high of $104.00 and a low of $54.00. Analyst consensus is Strong Buy, based on the latest ratings from 11 firms (9 buy, 2 hold, 0 sell). Over the past 90 days StreetAlpha recorded 1 whale options trade in IONS, 100% of them bullish and 0% bearish. In the past 30 days there were 5 dark pool prints totaling $9.5M, the largest $5.4M.
Each firm's latest rating on IONS in the past 90 days
Average 12-month target
$81.82
▲ 89.0% upside
Based on 11 analysts who set a price target on IONS in the past 90 days. The average target is $81.82, with a high of $104.00 and a low of $54.00, compared with the last close of $43.30.
Highest target$104.00
Average target$81.82
Lowest target$54.00
Latest rating changes
JP MorganTarget lowered
Sep 22Buy$76 → $70
GuggenheimMaintained
Sep 15Buy$80
BarclaysTarget lowered
Sep 9Buy$90 → $85
Morgan StanleyTarget lowered
Sep 8Buy$110 → $104
Goldman SachsTarget lowered
Sep 8Hold$75 → $56
Date
Firm
Action
Rating
Price target
Sep 22
JP Morgan
Target lowered
Buy
$76 → $70
Sep 15
Guggenheim
Maintained
Buy
$80
Sep 9
Barclays
Target lowered
Buy
$90 → $85
Sep 8
Morgan Stanley
Target lowered
Buy
$110 → $104
Sep 8
Goldman Sachs
Target lowered
Hold
$75 → $56
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Whale Options Flow
90D
Total alerts
1
Bullish
1
100%
Bearish
0
0%
Date span
Aug 10 – Aug 10
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Dark Pool
30D
Prints
5
Notional
$9.5M
Largest print
$5.4M
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AI Auto Pilots
Paper trading
StreetAlpha runs four autonomous AI traders powered by Anthropic's Claude. Each one reads options flow, dark pool prints, insider filings, sentiment, macro signals and technicals, then makes its own trading decisions in a paper portfolio. Every decision is logged and every trade is tracked, so you can see whether IONS is in one of them and how their past IONS trades turned out.
