HighVista Strategies
HighVista Strategies reported 147 stocks worth $439M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are DBC (6.4%), ABVX (3.4%) and RVMD (2.9%). Compared with Q1 2026, the fund opened new positions in CCCC, RLMD and TXN, added to DFTX, IMVT and PRAX, trimmed ABVX, RVMD and LQDA and sold out of JAZZ, NATL and CLH.
Holdings
| # | Stock | Value | Weight | Shares | Change | Shares, 8 qtrs | Held |
|---|---|---|---|---|---|---|---|
| 1 |  DBC Invsc DB Commodity Index | $28.2M | 6.4% | 1.1M | No change | 8 of 8 | |
| 2 |  ABVX Abivax SA | $15.1M | 3.4% | 113K | −223 (−0%) | 8 of 8 | |
| 3 |  RVMD Revolution Medicines Inc | $12.5M | 2.9% | 67K | −2,326 (−3%) | 8 of 8 | |
| 4 |  DFTX Definium Therapeutics Inc | $11.4M | 2.6% | 243K | +57K (+31%) | 2 of 8 | |
| 5 |  IMVT Immunovant Inc | $10.7M | 2.4% | 278K | +53K (+23%) | 6 of 8 | |
| 6 |  PRAX Praxis Precision Medicines I | $10.1M | 2.3% | 30K | +3,887 (+15%) | 8 of 8 | |
| 7 |  RLAY Relay Therapeutics Inc | $9.5M | 2.2% | 506K | +84K (+20%) | 5 of 8 | |
| 8 |  ALKS Alkermes PLC | $9.4M | 2.1% | 179K | +106K (+145%) | 7 of 8 | |
| 9 |  PCVX Vaxcyte Inc | $8.7M | 2.0% | 150K | +25K (+20%) | 8 of 8 | |
| 10 |  TNGX Tango Therapeutics Inc | $8.1M | 1.9% | 260K | +156K (+150%) | 2 of 8 |
Positions at Jun 30, 2026, as reported. Change is against the fund's Q1 2026 filing; weight is the share of the fund's reported stocks.
Sold out
held in Q1 2026, gone in Q2 2026| Stock | Value last quarter | Shares sold |
|---|---|---|
TERNS PHARMACEUTICALS INC | $6M | 114K |
NUVALENT INC | $5.8M | 57K |
SOLENO THERAPEUTICS INC | $5.5M | 165K |
APOGEE THERAPEUTICS INC | $3M | 36K |
 JAZZ Jazz Pharmaceuticals PLC | $2M | 11K |
🔒 Free account: see all 30.
Reported value
last 8 quartersThe value of the US stocks the fund reported, at quarter end prices. It moves with the market as well as with buying and selling.
Filings for Q2 2026
straight from the SEC| Filed | Form | Quarter | |
|---|---|---|---|
| Aug 14, 2026 | 13F-HR | Q2 2026 | SEC filing ↗ |
Other superinvestors
All hedge fund holdings →HighVista Strategies 13F FAQ
What does HighVista Strategies own?
HighVista Strategies reported 147 stocks worth $439M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are DBC (6.4%), ABVX (3.4%) and RVMD (2.9%). The table above lists every position in the filing (the top 10 without an account).
What did HighVista Strategies buy and sell in Q2 2026?
Compared with Q1 2026: 29 new positions, 50 added to, 66 trimmed and 38 sold out. New positions include CCCC, RLMD and TXN. It sold all of JAZZ, NATL and CLH.
When will HighVista Strategies file its next 13F?
Holdings as of Sep 30, 2026 are due by Nov 16, 2026. The filing appears on this page within minutes of reaching the SEC.
How much is HighVista Strategies's portfolio worth?
The Q2 2026 filing reports $439M in US stocks. That leaves out cash, bonds, short positions and most foreign holdings, so the fund's total assets are usually larger.
For informational and educational purposes only. Not investment advice, and not a recommendation to buy or sell any security. Holdings come from the fund's SEC Form 13F filings as reported and show positions at the end of the quarter, up to 45 days before the filing. The fund may have changed its positions since. A 13F leaves out short positions, cash, bonds and most foreign holdings. See all hedge fund holdings.