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13F holdings · Q2 2026

Foresite Capital Management VI

West Hollywood, CA · files as Foresite Capital Management VI LLC
Holdings as of Jun 30, 2026Filed Aug 14, 2026Next filing due Nov 16, 2026CIK 2013341

Foresite Capital Management VI reported 23 stocks worth $643M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are CGON (26.2%), ALMS (18.6%) and SPTX (6.0%). Compared with Q1 2026, the fund opened new positions in SPTX, PBLS and BEAM, added to CGON, DNLI and CLDX and sold out of OKUR.

Reported value$643M+39.6% vs last quarter
Stocks held238 new · 2 sold out
Top 5 weight61.5%very concentrated
Turnover37%of the portfolio changed
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Holdings

#StockValueWeightSharesChangeShares, 7 qtrsHeld
1
CGON
CG Oncology Inc
$168M26.2%2.4M+148K (+7%)7 of 7
2
ALMS
Alumis Inc
$120M18.6%4.2MNo change7 of 7
3
SPTX
Seaport Therapeutics Inc
$38.7M6.0%1.8MNew position1 of 7
4
DNLI
Denali Therapeutics Inc
$35.9M5.6%1.4M+187K (+15%)4 of 7
5
CLDX
Celldex Therapeutics Inc
$32.7M5.1%880K+564K (+178%)2 of 7
6
AGIO
Agios Pharmaceuticals Inc
$29.1M4.5%785K+260K (+50%)3 of 7
7
CRVS
Corvus Pharmaceuticals Inc
$27.4M4.3%1.8MNo change7 of 7
8
PBLS
Parabilis Medicines Inc Com
$27.3M4.3%999KNew position1 of 7
9
GHRS
GH Research PLC
$25.3M3.9%940K+625K (+198%)2 of 7
10
JBIO
Jade Biosciences Inc
$19.7M3.1%887K+567K (+177%)2 of 7
🔒 13 more holdings in this filing. Create a free account or sign in to see them all.

Positions at Jun 30, 2026, as reported. Change is against the fund's Q1 2026 filing; weight is the share of the fund's reported stocks.

Sold out

held in Q1 2026, gone in Q2 2026
StockValue last quarterShares sold
CENTESSA PHARMACEUTICALS PLC
$54.2M1.4M
OKUR
Onkure Therapeutics Inc
$6M1.4M

Reported value

last 7 quarters
$224MQ4 '24
$183MQ1 '25
$178MQ2 '25
$259MQ3 '25
$331MQ4 '25
$460MQ1 '26
$643MQ2 '26

The value of the US stocks the fund reported, at quarter end prices. It moves with the market as well as with buying and selling.

Filings for Q2 2026

straight from the SEC
FiledFormQuarter
Aug 14, 202613F-HRQ2 2026SEC filing ↗

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Foresite Capital Management VI 13F FAQ

What does Foresite Capital Management VI own?

Foresite Capital Management VI reported 23 stocks worth $643M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are CGON (26.2%), ALMS (18.6%) and SPTX (6.0%). The table above lists every position in the filing (the top 10 without an account).

What did Foresite Capital Management VI buy and sell in Q2 2026?

Compared with Q1 2026: 8 new positions, 6 added to, 0 trimmed and 2 sold out. New positions include SPTX, PBLS and BEAM. It sold all of OKUR.

When will Foresite Capital Management VI file its next 13F?

Holdings as of Sep 30, 2026 are due by Nov 16, 2026. The filing appears on this page within minutes of reaching the SEC.

How much is Foresite Capital Management VI's portfolio worth?

The Q2 2026 filing reports $643M in US stocks. That leaves out cash, bonds, short positions and most foreign holdings, so the fund's total assets are usually larger.

For informational and educational purposes only. Not investment advice, and not a recommendation to buy or sell any security. Holdings come from the fund's SEC Form 13F filings as reported and show positions at the end of the quarter, up to 45 days before the filing. The fund may have changed its positions since. A 13F leaves out short positions, cash, bonds and most foreign holdings. See all hedge fund holdings.