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13F holdings · Q2 2026

Foresite Capital Management IV

West Hollywood, CA · files as Foresite Capital Management IV, LLC
Holdings as of Jun 30, 2026Filed Aug 14, 2026Next filing due Nov 16, 2026CIK 1704132

Foresite Capital Management IV reported 6 stocks worth $290M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are PHVS (57.0%), CYTK (21.0%) and EIKN (8.7%). Compared with Q1 2026, the fund added to CYTK and RLAY and sold out of LYEL, ALEC and MAZE.

Reported value$290M+22.4% vs last quarter
Stocks held61 new · 3 sold out
Top 5 weight98.1%very concentrated
Turnover20%of the portfolio changed
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Holdings

#StockValueWeightSharesChangeShares, 8 qtrsHeld
1
PHVS
Pharvaris N V
$165M57.0%4.8MNo change8 of 8
2
CYTK
Cytokinetics Inc
$60.9M21.0%715K+211K (+42%)4 of 8
3
EIKN
Eikon Therapeutics Inc
$25.4M8.7%1.9MNo change2 of 8
4
RLAY
Relay Therapeutics Inc
$23.4M8.1%1.3M+250K (+25%)8 of 8
5
XENE
Xenon Pharmaceuticals Inc
$9.7M3.3%160KNo change5 of 8
6
CRINETICS PHARMACEUTICALS IN
$5.6M1.9%150KNew position1 of 8

Positions at Jun 30, 2026, as reported. Change is against the fund's Q1 2026 filing; weight is the share of the fund's reported stocks.

Sold out

held in Q1 2026, gone in Q2 2026
StockValue last quarterShares sold
LYEL
Lyell Immunopharma Inc
$16.1M800K
ALEC
Alector Inc
$8.4M3.9M
MAZE
Maze Therapeutics Inc
$4.7M157K

Reported value

last 8 quarters
$153MQ3 '24
$109MQ4 '24
$111MQ1 '25
$124MQ2 '25
$183MQ3 '25
$230MQ4 '25
$237MQ1 '26
$290MQ2 '26

The value of the US stocks the fund reported, at quarter end prices. It moves with the market as well as with buying and selling.

Filings for Q2 2026

straight from the SEC
FiledFormQuarter
Aug 14, 202613F-HRQ2 2026SEC filing ↗

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Foresite Capital Management IV 13F FAQ

What does Foresite Capital Management IV own?

Foresite Capital Management IV reported 6 stocks worth $290M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are PHVS (57.0%), CYTK (21.0%) and EIKN (8.7%). The table above lists every position in the filing (the top 10 without an account).

What did Foresite Capital Management IV buy and sell in Q2 2026?

Compared with Q1 2026: 1 new positions, 2 added to, 0 trimmed and 3 sold out. It sold all of LYEL, ALEC and MAZE.

When will Foresite Capital Management IV file its next 13F?

Holdings as of Sep 30, 2026 are due by Nov 16, 2026. The filing appears on this page within minutes of reaching the SEC.

How much is Foresite Capital Management IV's portfolio worth?

The Q2 2026 filing reports $290M in US stocks. That leaves out cash, bonds, short positions and most foreign holdings, so the fund's total assets are usually larger.

For informational and educational purposes only. Not investment advice, and not a recommendation to buy or sell any security. Holdings come from the fund's SEC Form 13F filings as reported and show positions at the end of the quarter, up to 45 days before the filing. The fund may have changed its positions since. A 13F leaves out short positions, cash, bonds and most foreign holdings. See all hedge fund holdings.