Casdin Capital
Casdin Capital reported 43 stocks worth $2B in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are RVMD (24.2%), RLAY (15.0%) and WGS (12.7%). Compared with Q1 2026, the fund opened new positions in PBLS, SION and SRPT, added to RLAY, WGS and DNLI, trimmed TXG and GH and sold out of QGEN, TEM and MLTX.
Holdings
| # | Stock | Value | Weight | Shares | Change | Shares, 8 qtrs | Held |
|---|---|---|---|---|---|---|---|
| 1 |  RVMD Revolution Medicines Inc | $483M | 24.2% | 2.6M | No change | 8 of 8 | |
| 2 |  RLAY Relay Therapeutics Inc | $300M | 15.0% | 16M | +1.6M (+11%) | 8 of 8 | |
| 3 |  WGS Genedx Holdings Corp | $254M | 12.7% | 3.7M | +700K (+23%) | 8 of 8 | |
| 4 | BIOLIFE SOLUTIONS INC | $131M | 6.6% | 4.7M | −1.3M (−22%) | 8 of 8 | |
| 5 |  ILMN Illumina Inc | $93.2M | 4.7% | 530K | No change | 8 of 8 | |
| 6 |  LAB Standard Biotools Inc | $73M | 3.7% | 88.8M | No change | 8 of 8 | |
| 7 |  GPCR Structure Therapeutics Inc | $63.1M | 3.2% | 1.2M | No change | 8 of 8 | |
| 8 |  DNLI Denali Therapeutics Inc | $52.6M | 2.6% | 2M | +205K (+11%) | 8 of 8 | |
| 9 |  NGNE Neurogene Inc | $48.6M | 2.4% | 1.5M | +125K (+9%) | 8 of 8 | |
| 10 |  BEAM Beam Therapeutics Inc | $46.3M | 2.3% | 1.4M | No change | 8 of 8 |
Positions at Jun 30, 2026, as reported. Change is against the fund's Q1 2026 filing; weight is the share of the fund's reported stocks.
Sold out
held in Q1 2026, gone in Q2 2026
Reported value
last 8 quartersThe value of the US stocks the fund reported, at quarter end prices. It moves with the market as well as with buying and selling.
Filings for Q2 2026
straight from the SEC| Filed | Form | Quarter | |
|---|---|---|---|
| Aug 14, 2026 | 13F-HR | Q2 2026 | SEC filing ↗ |
Other superinvestors
All hedge fund holdings →Casdin Capital 13F FAQ
What does Casdin Capital own?
Casdin Capital reported 43 stocks worth $2B in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are RVMD (24.2%), RLAY (15.0%) and WGS (12.7%). The table above lists every position in the filing (the top 10 without an account).
What did Casdin Capital buy and sell in Q2 2026?
Compared with Q1 2026: 6 new positions, 9 added to, 3 trimmed and 3 sold out. New positions include PBLS, SION and SRPT. It sold all of QGEN, TEM and MLTX.
When will Casdin Capital file its next 13F?
Holdings as of Sep 30, 2026 are due by Nov 16, 2026. The filing appears on this page within minutes of reaching the SEC.
How much is Casdin Capital's portfolio worth?
The Q2 2026 filing reports $2B in US stocks. That leaves out cash, bonds, short positions and most foreign holdings, so the fund's total assets are usually larger.
For informational and educational purposes only. Not investment advice, and not a recommendation to buy or sell any security. Holdings come from the fund's SEC Form 13F filings as reported and show positions at the end of the quarter, up to 45 days before the filing. The fund may have changed its positions since. A 13F leaves out short positions, cash, bonds and most foreign holdings. See all hedge fund holdings.