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13F holdings · Q2 2026

Avidity Partners Management

Dallas, TX · files as Avidity Partners Management LP
Holdings as of Jun 30, 2026Filed Aug 14, 2026Next filing due Nov 16, 2026CIK 1791827

Avidity Partners Management reported 45 stocks worth $624M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are DNTH (32.9%), CGON (15.9%) and ORKA (11.6%). Compared with Q1 2026, the fund opened new positions in MOBI, IMUX and SENS, added to CGON, TEM and GPCR, trimmed DNTH, ORKA and JBIO and sold out of IMUX, HUM and SCYX.

Reported value$624M−33.3% vs last quarter
Stocks held459 new · 16 sold out
Top 5 weight70.9%very concentrated
Turnover87%of the portfolio changed
🔒 A free account shows every holding, what the fund sold and its options.Create free account

Holdings

#StockValueWeightSharesChangeShares, 8 qtrsHeld
1
DNTH
Dianthus Therapeutics Inc
$205M32.9%2.1M−2.1M (−50%)8 of 8
2
CGON
CG Oncology Inc
$99.4M15.9%1.4M+110K (+9%)8 of 8
3
ORKA
Oruka Therapeutics Inc
$72.4M11.6%760K−760K (−50%)8 of 8
4
JBIO
Jade Biosciences Inc
$37.8M6.0%1.7M−1.1M (−39%)5 of 8
5
ELVN
Enliven Therapeutics Inc
$27.9M4.5%550K−250K (−31%)6 of 8
6
CATX
Perspective Therapeutics Inc
$21.5M3.4%6.3M−5.8M (−48%)8 of 8
7
AKTS
Aktis Oncology Inc
$15.6M2.5%484K−453K (−48%)2 of 8
8
PVLA
Palvella Therapeutics Inc NE
$10.7M1.7%70K−70K (−50%)3 of 8
9
MOBI
Mobia Med Inc
$10.7M1.7%798KNew position1 of 8
10
RGEN
Repligen Corp
$10.6M1.7%78K−78K (−50%)5 of 8
🔒 35 more holdings in this filing. Create a free account or sign in to see them all.

Positions at Jun 30, 2026, as reported. Change is against the fund's Q1 2026 filing; weight is the share of the fund's reported stocks.

Sold out

held in Q1 2026, gone in Q2 2026
StockValue last quarterShares sold
IMUX
Immunic Inc
$13.9M7.4M
HUM
Humana Inc
$5.9M25K
SCYX
Scynexis Inc
$3.8M4.2M
ICLR
Icon PLC
$3.7M32K
NTRA
Natera Inc
$3.7M18K

🔒 Free account: see all 16.

Reported value

last 8 quarters
$2BQ3 '24
$1BQ4 '24
$485MQ1 '25
$499MQ2 '25
$439MQ3 '25
$347MQ4 '25
$936MQ1 '26
$624MQ2 '26

The value of the US stocks the fund reported, at quarter end prices. It moves with the market as well as with buying and selling.

Filings for Q2 2026

straight from the SEC
FiledFormQuarter
Aug 14, 202613F-HRQ2 2026SEC filing ↗

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Avidity Partners Management 13F FAQ

What does Avidity Partners Management own?

Avidity Partners Management reported 45 stocks worth $624M in its 13F filing for Q2 2026, filed Aug 14, 2026. Its largest holdings are DNTH (32.9%), CGON (15.9%) and ORKA (11.6%). The table above lists every position in the filing (the top 10 without an account).

What did Avidity Partners Management buy and sell in Q2 2026?

Compared with Q1 2026: 9 new positions, 4 added to, 27 trimmed and 16 sold out. New positions include MOBI, IMUX and SENS. It sold all of IMUX, HUM and SCYX.

When will Avidity Partners Management file its next 13F?

Holdings as of Sep 30, 2026 are due by Nov 16, 2026. The filing appears on this page within minutes of reaching the SEC.

How much is Avidity Partners Management's portfolio worth?

The Q2 2026 filing reports $624M in US stocks. That leaves out cash, bonds, short positions and most foreign holdings, so the fund's total assets are usually larger.

For informational and educational purposes only. Not investment advice, and not a recommendation to buy or sell any security. Holdings come from the fund's SEC Form 13F filings as reported and show positions at the end of the quarter, up to 45 days before the filing. The fund may have changed its positions since. A 13F leaves out short positions, cash, bonds and most foreign holdings. See all hedge fund holdings.