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Spyre Therapeutics, Inc. (SYRE)

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Spyre Therapeutics develops antibody drugs for inflammatory bowel disease and rheumatic conditions. SYRE reports earnings on Tue, Nov 3, 2026. Analyst consensus is Strong Buy, based on the latest ratings from 7 firms (7 buy, 0 hold, 0 sell). Over the past 90 days StreetAlpha recorded 1 whale options trade in SYRE, 100% of them bullish and 0% bearish.

Prices, price targets and earnings estimates for SYRE are shown to AI Starter and AI Pro members. Ratings, flow and news are open to everyone.See plans
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Next report
Nov 3
2026 · Time not announced
Consensus EPS forecast
EPS and revenue estimates
Year-ago EPS
Same quarter last year
Options-implied move
Move priced in by options
Analyst consensus
Strong Buy
Based on 7 analyst ratings (90 days)
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Analyst Ratings & Price Targets

Analyst Ratings →
Consensus · 90 days
Strong Buy
7firms
7 Buy0 Hold0 Sell
Each firm's latest rating on SYRE in the past 90 days
Average 12-month target
Price targets for SYREThe average, highest and lowest analyst targets and the target chart are shown to AI Starter and AI Pro members.See plans
Latest rating changes
UBSInitiated
Oct 12Buy
JP MorganInitiated
Oct 1Buy
BTIGReiterated
Oct 1Buy
Deutsche BankTarget lowered
Aug 26Buy
WedbushTarget lowered
Aug 26Buy
DateFirmActionRatingPrice target
Oct 12UBSInitiatedBuy
Oct 1JP MorganInitiatedBuy
Oct 1BTIGReiteratedBuy
Aug 26Deutsche BankTarget loweredBuy
Aug 26WedbushTarget loweredBuy
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Whale Options Flow

90D
Total alerts
1
Bullish
1
100%
Bearish
0
0%
Date span
Aug 6 – Aug 6
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Paper trading

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SYRE in the AI portfolios
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Macro & Market News

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About Spyre Therapeutics

Spyre Therapeutics is a biotechnology company based in Waltham, Massachusetts, that develops antibody medicines. Its drug candidates are designed to act on the immune system and to last longer between doses, with the aim of treating inflammatory bowel disease, which includes ulcerative colitis and Crohn's disease. The company is also studying its anti-TL1A antibody for rheumatic conditions such as rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis. Its target patients are people living with these chronic immune conditions, and its products are still in development rather than on the market.

Headquarters
Waltham, MA
Founded
2013