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Spruce Biosciences, Inc. (SPRB)

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Spruce Biosciences develops therapies for neurological disorders, led by an enzyme replacement therapy for a rare genetic brain disease. SPRB reports earnings on Mon, Nov 9, 2026. Analyst consensus is Strong Buy, based on the latest ratings from 3 firms (3 buy, 0 hold, 0 sell).

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Next report
Nov 9
2026 · Time not announced
Consensus EPS forecast
EPS and revenue estimates
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Analyst consensus
Strong Buy
Based on 3 analyst ratings (90 days)
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Analyst Ratings & Price Targets

Analyst Ratings →
Consensus · 90 days
Strong Buy
3firms
3 Buy0 Hold0 Sell
Each firm's latest rating on SPRB in the past 90 days
Average 12-month target
Price targets for SPRBThe average, highest and lowest analyst targets and the target chart are shown to AI Starter and AI Pro members.See plans
Latest rating changes
Lake StreetInitiated
Sep 17Buy
GuggenheimTarget lowered
Aug 17Buy
CitizensMaintained
Aug 13Buy
B. Riley SecuritiesInitiated
Jul 13Buy
GuggenheimInitiated
Jun 16Buy
DateFirmActionRatingPrice target
Sep 17Lake StreetInitiatedBuy
Aug 17GuggenheimTarget loweredBuy
Aug 13CitizensMaintainedBuy
Jul 13B. Riley SecuritiesInitiatedBuy
Jun 16GuggenheimInitiatedBuy
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Seasonality

How SPRB has done in each calendar month: the average and median return, how often each month finished higher, and every year since 2020.

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Whale Options Flow

90D

No whale options trades in SPRB in the last 90 days.

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About Spruce Biosciences

Spruce Biosciences is a biopharmaceutical company that develops therapies for neurological disorders. Its lead product candidate, TA-ERT, is an enzyme replacement therapy under development for MPS IIIB, a rare genetic disease that causes progressive brain damage and has no approved treatments. The therapy is designed to be delivered directly into the central nervous system, and its intended customers are patients with the disease and the clinicians who treat them. The company is based in South San Francisco, California.

Headquarters
South San Francisco, CA